Data Integrity Check:

• Checking sample names - spaces will replaced with underscore, and special characters will be removed;
• Checking the class labels - at least three replicates are required in each class.
• The data (except class labels) must not contain non-numeric values.
• If the samples are paired, the pair labels must conform to the specified format.
• The presence of missing values or features with constant values (i.e. all zeros).