Normalization Overview:

The normalization procedures are grouped into three categories. You can use one or combine them to achieve better results.

  • Sample normalization is for general-purpose adjustment for systematic differences among samples;
  • Data transformation applies a mathematical transformation on individual values themselves. A simple mathematical approach is used to deal with negative values in log and square root Please search OmicsForum using "normalization #metaboanalyst" to find more information.
  • Data scaling adjusts each variable/feature by a scaling factor computed based on the dispersion of the variable.

Sample normalization
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Data transformation
Data scaling